The positive percentage of p-Akt, p-4EBP1 and p-p70S6K expression in the NPC and the non-cancerous nasopharyngeal control tissue was 47.2% (117/248), 73.0% (181/248), 61.7% (153/248), 33.3% (22/66), 59.1% (39/66) and 47.0% (31/66), respectively. The gene discussed is EIF4EBP1; the disease is nasopharyngeal carcinoma.