MTOR and nasopharyngeal carcinoma: It appears that multiple factors are involved in the carcinogenesis of NPC ranging from Epstein-Barr virus (EBV) infection, environmental factors and genetic susceptibility, to the aberrant expression of oncogenes/tumor-suppressor genes and the abnormal activation of signaling pathways such as Akt/mTOR pathway, mitogen-activated protein kinases and Wnt signaling pathway [1]–[2].