Recently a large-scale GWAS analysis of more than 17,000 AMD cases indicated 19 other AMD loci, in which 7 loci were novel and near the genes IER3-DDR1, COL8A1-FILIP1L, SLC16A8, TGFBR1, ADAMTS9, RAD51B, and B3GALTL [18]. The gene discussed is IER3; the disease is age-related macular degeneration.