The mean plasma levels of VEGF was statistically higher in AMD patients (84.22 pg/ml) than in controls (15 pg/ml), and in active form of AMD patients (83.39 pg/ml) compared to those with a scar form (30.60 pg/ml) (p = 0.04 and p = 0.035, respectively) (Figure 1). This evidence concerns the gene VEGFA and age-related macular degeneration.