For males, a higher risk of elevated CRP was observed in particular in patients with no regular physical activity (aRR 1.5 (95% CI 1.1-1.9)) compared to males with regular physical activity, and in those with previous cardiovascular disease (aRR 1.5 (95% CI 1.2-1.9) compared to no cardiovascular disease. The gene discussed is CRP; the disease is cardiovascular disorder.