IGHA1 and IgA glomerulonephritis: Genetic factors are suspected in the pathogenesis of IgA nephropathy: (i) the prevalence of IgA nephropathy varies between ethnic group [3], (ii) familial clustering consistent with autosomal dominant transmission with incomplete penetrance [4-6] (iii) inherited aberrant IgA1 glycosylation in familial and sporadic IgA nephropathy [7].