Regarding MM patients, a panel of 10 cytokines, MIF, MIG (p<0.05); IL-2Ra, SCGF-β, IL-8, (p<0.01); HGF, M-CSF, SDF-1α, IL-4, MIP-1α (p<0.001), was found down-regulated with respect to the control group. This evidence concerns the gene MIF and Miyoshi myopathy.