Many genetic alterations that contribute to CRC have been identified including mutations which inactivate tumor suppressor genes (e.g. p53 and APC mutated in 52% and 76% of tumors, respectively) or activate oncogenes (e.g. KRAS and BRAF mutated in 42% and 10% of tumors, respectively) [2], [3]. Here, KRAS is linked to colorectal carcinoma.