E2F1 and breast carcinoma: Upregulation of the activating E2F genes was also found in basal versus not-basal breast cancer: E2F1 (FC = 2.01, P = 8.72E-06), E2F2 (FC = 1.98, P = 2.97E-07), and E2F3 (FC = 1.95, P = 8.13E-17; Table 3).