Similarly, whether overexpression of hnRNP A2/B1, P68/DDX5, DROSHA-DGCR8, or CUGBP1 rescues any phenotype in mouse models expressing expanded CGG repeats, would be necessary to determine the importance of these candidate proteins to FXTAS pathology. This evidence concerns the gene CELF1 and fragile X-associated tremor/ataxia syndrome.