Similarly, whether overexpression of hnRNP A2/B1, P68/DDX5, DROSHA-DGCR8, or CUGBP1 rescues any phenotype in mouse models expressing expanded CGG repeats, would be necessary to determine the importance of these candidate proteins to FXTAS pathology. The gene discussed is DDX5; the disease is fragile X-associated tremor/ataxia syndrome.