Classical and wild-derived strains of mice exhibit a range of susceptibilities to Salmonella infection; for example, the C57BL/6J classical inbred strain are extremely susceptible to infection with Salmonella typhimurium due to a mutation in Slc11a1 (solute carrier family 11 member 1), while the 129 sub-strains are highly resistant (14). This evidence concerns the gene SLC11A1 and infection.