The retention of albumin in tumors has since been observed in various experimental solid tumors (e.g., sarcoma, ovarian carcinoma, Novikof hepatoma, etc.)using radiolabeled- or dye-complexed serum albumin (Peterson and Appelgren, 1973; Sinn et al., 1990; Andersson et al., 1991; Schilling et al., 1992; Stehle et al., 1997; Wunder et al., 1997). This evidence concerns the gene ALB and hepatocellular carcinoma.