Considering Dp44mT targets lysosomes to induce apoptosis (Lovejoy et al., 2011), and that HSA potentially undergoes lysosomal catabolism in tumors (Andersson et al., 1991; Stehle et al., 1997), it can be hypothesized that HSA facilitates Dp44mT delivery to the lysosomes, enhancing its anti-cancer activity (Merlot and Richardson, 2014). The gene discussed is ALB; the disease is cancer.