IL23R and Crohn disease: In contrast to the L310P polymorphism in IL23R gene, which confers protection to individuals with the TT genotype and T allele against the development of Crohn’s disease, with respective odds ratio 0.26 (CI: 0.01-5.19, P = 0.38) and 0.74 (CI: 0.31-1.73, P = 0.48) (Table 4).