To this end, uPAR was first overexpressed in the murine OSCC cell line AT84 (figure 1), and cells were analysed in vitro in cell culture, in vivo as tongue and skin tumours (figure 2 and figure S3), and ex vivo when invading leiomyoma tissue (figure 5 and 8). The gene discussed is PLAUR; the disease is leiomyoma.