Another interesting study from Jeong et al, 2009 [14], demonstrated the inhibition of Leukotriene A4 hydrolase, the terminal enzyme in the Leukoteriene B4 synthesis, as the site of action of [6]-gingerol in inhibiting the anchorage dependent growth of HCT116 colon cancer cells in culture and in xenograft model. Here, LTA4H is linked to malignant colon neoplasm.