In prostate, but also breast, endometrial and hepatocellular carcinomas, another early tumor marker is GSTP1 promoter methylation which is detected at various percentages of clinical samples (Esteller et al., 1998; Zhong et al., 2002; Chan et al., 2005; Lee, 2007; Yoon et al., 2012). This evidence concerns the gene GSTP1 and neoplasm.