IFNG and parasitic infectious disease: Lower level of parasitemia was also observed in IFN-γ treated SW mice that were infected with lethal strain of P. yoelii. In addition, these treated mice also exhibited better survival outcome [94]. P. chabaudi AS-infected mice treated with monoclonal antibody against IFN-γ had less control of parasite multiplication [195], once again suggesting that IFN-γ is essential for limiting parasite growth.