UBE3A and neoplasm: Another oncogenic ubiquitin ligase, UBE3A (aka E6-AP; marks TP53 for proteolysis degradation) was placed under control of the AR via fusion to the first exon of androgen responsive gene SLC45A3 in T11, although UBE3A was not expressed at an outlier level in this tumor at the time of prostatectomy.