ZEB1 and Fuchs endothelial corneal dystrophy: To date, three genes, ZEB1 (TCF8), encoding the zinc finger E-box-binding homeobox 1 transcription factor, SLC4A11, coding for a sodium-borate cotransporter, and LOXHD1, encoding lipoxygenase homology domain 1 were found to be involved in the development of more common late-onset FECD [33,34,35].