CD8A and acne: We defined the markers of T cell subsets at mRNA level and studied Th1 (T-bet), Th17 (IL-17A), Treg (Foxp3) cells, cytotoxic CD8+ T-cells and CD68 macrophages and CD83 positive activated dendritic cells in clinically early acne lesions by immunohistochemistry both phenotypically and proportionally (Figure 5, Table 7).