The expression of cytokines IL-6, IL-12p40, INF-γ and TGF-β have not been studied earlier in acne lesions as also noticed by Thiboutot and co-workers [19], nor cytokines IL-17A, IL-17F, IL-23p19, IL-22 and chemokines CCL20 and CSF2. Here, IL22 is linked to acne.