We defined the markers of T cell subsets at mRNA level and studied Th1 (T-bet), Th17 (IL-17A), Treg (Foxp3) cells, cytotoxic CD8+ T-cells and CD68 macrophages and CD83 positive activated dendritic cells in clinically early acne lesions by immunohistochemistry both phenotypically and proportionally (Figure 5, Table 7). Here, CD83 is linked to acne.