CXCR4 and atherosclerosis: In a murine model of atherosclerosis the inhibition of the CXCR4-CXCL12 axis by AMD or transplantation of CXCR4 deficient bone marrow led to an increased number of circulating leukocytes (predominantly neutrophils) correlating with atherosclerotic lesions (Zernecke et al., 2008).