The observed discrepancy in the number of CCL2 positive cells in hippocampal WM/WML versus GM/GML is in line with the observation that CCL2 mRNA levels are significantly higher within the corpus callosum (WM) compared to the cortex (GM) in both control mice as well as a mouse model for MS, e.g. cuprizone treated mice [58]. Here, CCL2 is linked to myeloid sarcoma.