In contrast, a significant reduction (P < 0.01) of ~3.8 folds (IL-1ß), ~3.97 folds (TNFa) and ~4.9 folds (IL-10) was seen in depolymerase + gentamicin treated group (Figure 3a, b, c) on peak day of infection (day 3). The gene discussed is TNF; the disease is infection.