UNC5B and neoplasm: Lejmi et al.[16] reported that neogenin was upregulated in vascular endothelial growth factor-stimulated endothelial cells, choroidal neovessels, and tumor angiogenesis, while silencing of either neogenin or UNC5B abolished netrin-4′s inhibitory effect on endothelial cell migration, choroidal neovascularization, and tumor angiogenesis.