In addition to miR-139-5p, other miRNAs (miR-34a, miR-144) were also reported to inhibit NOTCH1 in CRC (Sureban et al. 2011; Bu et al. 2013), indicating that there is a significant cross-talk between NOTCH and miRNAs (Mo et al. 2013). This evidence concerns the gene NOTCH1 and colorectal carcinoma.