Pearson's Correlation test was performed in two matched groups: i) cirrhotic tissues staining with phospho-Met and phospho-CAV1; ii) HCC tissues staining with phospho-Met and phospho-CAV1 analysis revealed that phospho-CAV1 expression was correlated positively with phospho-Met in cirrhosis (r = 0.70, p<0.0001) and HCC (r = 0.73, p<0.0001). This evidence concerns the gene CAV1 and hepatocellular carcinoma.