In particular, ANTXR1 (also known as tumor endothelial marker 8, TEM8) is expressed in the mouse dentate gyrus granule cell layer (Allen atlas; http://mouse.brain-map.org/gene/show/45380) and has been reported to promote cell spreading in human tumor tissues [20],[21]: therefore, it was hypothesized that reduced expression of miR487a will increase ANTXR1 levels, leading to granule cell spreading (i.e. dispersion or bilamination, i.e. GCP 2). This evidence concerns the gene ANTXR1 and neoplasm.