Taking into account several reports demonstrating that interleukin- (IL-) 8, GRO, chemokine (C-C motif) ligand (CCL)-2, and IL-6 are among the most relevant factors in HCC [17], we decided to evaluate by qPCR the expression of CXCR1, CXCR2, CCR2, IL-6R, and IL-6ST. The gene discussed is CXCR2; the disease is hepatocellular carcinoma.