We have previously assembled evidence that null mutation of GAD65 results in a PTSD-like behavioral phenotype in fear conditioned mice (Stork et al., 2003; Bergado-Acosta et al., 2008; Sangha et al., 2009) and Heldt and Ressler (2007) showed a correlation of intra-amygdalar GAD67 expression with the level of conditioned fear in rats (Heldt and Ressler, 2007). Here, GAD2 is linked to post-traumatic stress disorder.