Moreover, an SNP in the gene encoding the receptor, FcγRIIB [Ile232Thr (I232T)], leads to a non-functional receptor and is strongly associated with SLE in populations from Asia and of Asian descent (Floto et al., 2005; Kono et al., 2005; Kyogoku et al., 2002; Lee et al., 2009b; Siriboonrit et al., 2003). The gene discussed is FCGR2B; the disease is systemic lupus erythematosus.