TBL1XR1 and nasopharyngeal carcinoma: To validate whether the upregulation of TBL1XR1 in NPC cell lines was clinically relevant, we also examined protein and mRNA levels in NPC tissues.TBL1XR1 was found to be overexpressed to varying degrees in all 10 NPC samples (Figure 1C), and was barely detectable in the three healthy nasopharyngeal epithelial tissue samples.