All sixteen SNPs, which were significantly associated with type 2 diabetes in South Asians, were included in the genotype score (ADCY5, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B, FTO, GLIS3, HHEX, PPARG, SLC30A8, TCF7L2 rs7903146 and rs12255372, CHCHD9, KCNQ1 rs2237892 and rs2237897, IGF2BP2 and HMG20A SNPs from Table 1 and Fig. 2). The gene discussed is ADCY5; the disease is type 2 diabetes mellitus.