Surprisingly, the risk alleles for both KCNQ1 polymorphisms substantially increased the odds of type 2 diabetes (rs2237892 OR 1.62, 95% CI 1.01–2.59; rs2237897 OR 2.19, 95% CI 1.25–3.82). The gene discussed is KCNQ1; the disease is type 2 diabetes mellitus.