Mutations in r-proteins have been linked to Diamond-Blackfan anemia (DBA), a rare congenital red blood cell aplasia (Ellis and Lipton, 2008; Ganapathi and Shimamura, 2008; Narla and Ebert, 2010; Ellis and Gleizes, 2011; McCann and Baserga, 2013; Ellis, 2014). The gene discussed is TCN1; the disease is Blackfan-Diamond anemia.