RELA and viral infectious disease: The enhanced activity ofNF-κB preceding apoptosis has been previously reported,notably during viral infections,24chemotherapy,33 or cytokinedeprivation.27 One possibleregulatory mechanism for NF-κB is the caspase-dependent cleavageof p65/RelA,23, 24, 25, 26, 27 and we observedthat p65/RelA was cleaved at a putative caspase-6 consensus recognitionsite.