CYP2W1 and adrenal cortex carcinoma: When considering separately the 72 patients with ACC treated with mitotane only (either as adjuvant or palliative therapy), we observed a slightly longer OS (median 131 vs 72 months, HR = 1.61, P = 0.17, Table 2) and time to progression (TTP, median 45 vs 24 months, HR = 1.37, P = 0.29 Table 2) for tumors with high CYP2W1 immunoreactivity.