In our study, profiles with low ALT, high IL-10, low IFN-γ and low IFN-γ:IL-10 ratio in major stress/anxiety patients is a typical characteristic of persistent infection, while the profiles with high ALT, low IL-10, high IFN-γ and high IFN-γ:IL-10 ratio in minor stress/anxiety patients prone to immunity activation and maybe virus clearance. Here, IL10 is linked to Anxiety.