Univariate analyses showed significant differences in patient survival and tumor relapse between patients with high and low nuclear expression of LSD1 (OS: p = 0.002, HR = 1.42, 95% CI = 1.13-1.77; RFS: p = 0.001, HR = 1.55, 95% CI = 1.20-1.99) and SIRT1 (RFS: p = 0.03, HR = 1.32, 95% CI = 1.03-1.70) (Figures 4A,4C and4D). This evidence concerns the gene KDM1A and neoplasm.