PARP1 and adenocarcinoma: Before analyzing the cell killing effects of a PARPi and ionizing radiation, we investigated the expression of three members of the PARP family and poly(ADP-ribose) glycohydrolase (PARG) and PARP enzymatic activity profiles in a panel of liver cancer cell lines and PHHs: HepG2, Huh7, FOCUS are hepatoma cell lines, SKHep1 an adenocarcinoma cell line, HepaRG a non-tumorigenic hepatoma cell line and HepG2 2.2.15 is a clone of HepG2 cells harboring in its genome four tandem copies of the hepatitis B virus (HBV) genome.