CSF2 and neoplasm: The survival and suppressive function of MDSCs are supported by tumor-produced myelopoietic growth factors including granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-6, granulocyte colony-stimulating factor (G-CSF) and others[14, 15], but some of these factors might also be produced at inflammatory sites[16–18].