In contrast, the inhibitors of PI3K/Akt (Ly294002, 0.016 mM) and NF-κB (Bay, 0.0032 mM), used as positive controls, significantly inhibited the growth of not only lung cancer cell lines but also normal MRC-5 cells (Fig. 2B, 2C). The gene discussed is NFKB1; the disease is lung cancer.