PTPRD inactivation is common in human malignancies and occurs in a number of cancer types including colorectal, esophageal adenocarcinoma, neuroblastoma, renal cell carcinoma, Ewing sarcoma, chronic myeloid leukemia, squamous cell carcinoma of the vulva, breast, lung cancer, melanoma, and glioblastoma [1,2,3,4,5,6,7,8,9,10,11]. The gene discussed is PTPRD; the disease is glioblastoma.