In our study, we selected VEGF index for assessment of endothelial function because it has been demonstrated that although VEGF-A can stimulate endothelial cell survival, endothelial migration and proliferation, generation of nitric oxide, mitosis of endothelial cells, the induction of angiogenesis, and vasodilatation [22], the level of VEGF has been associated with atherosclerosis progression and lesion destabilization. The gene discussed is VEGFA; the disease is atherosclerosis.