Moreover, several proteins involved in telomere maintenance [63-65] are present in the intranuclear inclusions characteristic of FXTAS (for example, lamin A/C, Ku80, γH2AX) [18] and could account for shorter telomere length demonstrated in patients with FXTAS [66,67]. The gene discussed is XRCC5; the disease is fragile X-associated tremor/ataxia syndrome.