Mutations in various proteins such as LRRK2, PARK2), phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1), and (DJ-1) have been observed in familiar cases of Parkinson, which only account for 10–15% of diagnosed cases (Hirsch et al., 2003; Rappold and Tieu, 2010; Pan-Montojo et al., 2010; Wang et al., 2011). This evidence concerns the gene PINK1 and Parkinsonism.