From these studies it is known that infection of colon epithelial cells (CEC) with Salmonella typhimurium causes an increase in GSK3β-dependent β-catenin phosphorylation, leading to an upregulation of IL-6, IL-8, and Wnt2, via TLR5/NF-κB activation [10, 14]. The gene discussed is IL6; the disease is infection.