However, Treg levels were significantly lower in patients with joint involvement 1.14% (0.1–3.7) as compared to patients without arthritis, 1.69% (0.4–5.4), P = 0.04, while no difference was observed considering CLA T cells: 1.4% (0.2−3.7) in patients with and 1.7% (0.4–5.4) in patients without joint involvement, P = 0.86. This evidence concerns the gene SELPLG and arthritic joint disease.