MMP3 was elevated significantly in both schistosomal bladder cancer (0.169 ng/ml) and non schistosomal bladder cancer groups (0.269 ng/ml) compared to the control group (P < 0,001); with more significant increase in non schistosomal bladder cancer than schistosomal bladder cancer patients. This evidence concerns the gene MMP3 and urinary bladder carcinoma.