VIM and breast cancer: In addition, if this link holds true in human breast cancer, it may be possible to identify women who are more susceptible to poor prognosis cancers based on the expression of these newly identified HFD-induced basal-like characteristics such as the mesenchymal marker Vimentin. Importantly, vimentin has been shown to play a significant role in the epithelial-mesenchymal transition (EMT) process in BC [46, 47].