FN1 and lymphangioleiomyomatosis: Taking our results (decreased fibronectin in LAM serum and an increase in the deposition in lung tissue of LAM patients) into account, combined with these previous findings, there is an indication that there is an imbalance existing in LAM with regard to the relationship between circulating soluble levels of fibronectin and the deposited levels of insoluble fibronectin in the lung.