Third, IL6 polymorphisms and in particular the −174 G/C variant were previously associated with various cardiovascular disease outcomes and risk factors, including ischemic cerebrovascular events [36], coronary heart disease [37], [38], high blood pressure [37], [39], total cholesterol, LDL, fasting glucose, BMI [40], carotid artery compliance and carotid intima media thickness [39], [41] as well as arterial stiffness and pulse pressure [42]. The gene discussed is IL6; the disease is cardiovascular disorder.