GWAS has identified a few susceptibility variants in glioblastoma or glioma; 12 loci at the regions of 20q13.33 (RTEL1), 5p15.33 (TERT), 9p21.3 (CDKN2BAS), 7p11.2 (EGFR), 8q24.21 (CCDC26), and 11q23.3 (PHLDB1) [22]–[23] have been collected in the NHGRI GWAS catalog (http://www.genome.gov/gwastudies/). This evidence concerns the gene TERT and central nervous system cancer.